Here was the specific question:
Let’s say my site has been touching different topics at once, and I decided to focus on one topic (i.e. doctor profiles, but before i had pages about diseases and hospitals). How would Google see this change? IMO, it’s an improvement, but would Google see?
John Mueller from Google sees this as a natural evolution from a website. He doesn’t recommend creating entirely new sites just for changing or altering the site’s topic area. But he also says that this is nothing that site owners should “shy away” from doing.
"That is kind of a normal change on a website. The themes of a website change over time, that’s not something that I’d say you’d need to shy away from or create separate sites if you want to touch upon a new topic. So that’s something, personally I see that as kind of a normal organic change of a website where maybe you expand on some areas, you kind of contract on other areas, focus more here, go a bit broader there, that’s totally natural, that’s not something I’d kind of shy away from."
How Google Handles a Site When It Changes Topic Focus
