Selected answers from the Dumb SEO Questions Facebook & G+ community.
Jim Munro: It`s hard to give evidence but if .co did have an influence, it is more like to be negative. It`s .co as in Colombia, not .co as in Company.
Jim Munro: Sometimes users form instant opinions and associations based on the domain and that in turn affects their click through rate and/or time on site. Generally .co domains are used by lowest-tier businesses (opinion). Spoiler alert: Some people will argue against this and everything else mentioned in this answer.
Christina Hutarso: Jim Munro hi Jim! Thanks for your opinion, I’ll keep this in mind. Got a bit overwhelmed when I did the research so would love to hear people’s opinion/ experience
Richard Hearne: There is a group of ccTLDs (including .co) that Google treats as gTLDs. See here: