Will a huge amount of link from one domain with an over-optimized anchor text put your site at any risk?

Selected answers from the Dumb SEO Questions Facebook & G+ community.

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  Nebojsa Djukic: Search engines should ignore noindex pages, so you shouldn't be worried. I'm just not sure if all SE treat noindex pages on the same way.
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  Nishant Desai: Site has no risk.. Nothing to worry..!
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  Jim Munro: Guys, I am not an expert so we should wait for confirmation but I think noindex simply means noindex.
  
  In almost all cases, a noindexed page will not appear in the index (although some pages might intermittently appear for a period).
  
  nofollow ;prevents Googlebot from following links from the page (I'm not sure that this completely prevents the passing of all pagerank value) ;
  
  If the concern is to mitigate Penguin, then I think the pages should 410/404, not noindex,nofollow.
  
  https://support.google.com/webmasters/answer/79812?hl=en
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  Daniel Duckworth: noindex is a way for large websites to tell Google not to index certain pages. This could be repetitious product categories for ecommerce sites or it could be landing pages that have slight variations for different audiences. On my site we use nonidex for the purpose built landing pages that we use with AdWords but don't want indexed. Having repitious content is a duplicate content issue.
  
  Nofollow is different in that the links on a page do not pass link juice to the target website. This should be used for sponsored links and press releases.
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  Daniel Duckworth: A redirect is different again. If the page has links pointing to it (it has some SEO value) then it should be redirected so it passes on it links juice.
  
  Noindex is not a guarantee that other search engines or web crawlers will not index the page. It's still publicly accessible.
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  Justin Y: I agree with Jim.
  If you don't want the domain to have a negative affect on yours, why not disavow it and move on? If you don't use it, lose it.
  That's my opinion.
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  Daniel Duckworth: Yeah disavow should be easy if export the links from something like the moz tools
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  Anna Gaw?cka: +Daniel Duckworth Not sure you can export any more than 10k links in OSE. And there is way more than that from the given domain. I'll look for an alternative tool, thanks!
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  Anna Gaw?cka: Maybe I'm paranoid, but if I can't have them nofollowed I'd rather disavow them.
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  Nebojsa Djukic: Is it a good idea to simply change the permalink of the page? If many spammy links points to the page: YourDomain.com/page perhaps she can change the permalink to YourDomain.com/new-page and spammy links will point to a page that doesn't exist. What do you think?
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  Anna Gaw?cka: +Nebojsa Djukic No, that's not an option. I was wondering if we actually need to ask for nofollowing them if the page is noindex nofollow anyway. Just for safety sake I'd rather do that and hopefully won't have to disavow ~100k links.
  Thanks everyone!